Restless Legs Syndrome (RLS) and Periodic limb movement during sleep (PLMS): 하지불안증후군

• 다중생리시스템 분석을 통한 주기적사지움직임증의 병태 생리와 심혈관계에 대한 영향 연구

       Multi-physiological system analysis for periodic limb movement and its influence upon cardiovascular system

• 하지불안증후군 환자에서 월경주기에 따른 증상의 변화
  

Severity of restless legs syndrome across menstrual cycle

• PLMS pathophysiology
  

• functional connectivity during PLMS

• source localization of EEG in relation to PLMS

• sleep spindles, K complexes and slow oscillation in RLS with/without PLMS

REM sleep behavior disorder (RBD): 렘수면행동장애

• 다중신경신호 기반 렘수면행동장애의 병태생리 기전 연구 및 신경퇴행질환에 대한 뉴로마커 발굴
  

Multineural signal based study on pathogenesis of REM sleep behavior disorder and identification of neuromarker for neurodegenerative disease

• functional connectivity of EEG resting state network 

• event-related potentials during visuospatial attentioin task 

• reduced P300 amplitude in iRBD compared with controls

• impaired inhibition of return (IOR) in iRBD
  

• EEG spectral characteristics of REM sleep EEG: phasic vs. tonic REM period

• 한국판 RBD 진단 설문지 개발

The REM sleep behavior disorder screening questionnaire: Validation study of a Korean version (RBDQ-KR)

• 멜라토닌의 렘수면행동장에 대한 효과
  

Effect of Slow-release Melatonin (Circadin®) Therapy on Idiopathic RBD: a Pilot Study

 
https://clinicaltrials.gov/ct2/show/NCT02836743?term=circadin&rank=4 

• RBD 다기관 전향적 환자 관찰 연구: RBD 코호트 연구
  

http://www.krbd.or.kr/ 

비침습적 뇌자극 치료 임상 연구

• 만성불면증에서 경두개전기자극의 효과  
  

Effect of Transcranial Direct-current Stimulation Therapy on Primary Chronic Insomnia Patients 

https://clinicaltrials.gov/ct2/show/NCT02832804?term=tDCS+insomnia&rank=1

약물이 뇌파에 미치는 영향 연구 (Pharmaco-EEG study)

• Effect of perampanel on cognition and EEG

• 알츠하이머치매에서 Choline Alfoscerate이 인지와 뇌파에 미치는 영향